The Foundation for Research and Technology-Hellas is the largest research center in Greece with well-organized facilities and highly qualified personnel. The Institute of Molecular Biology and Biotechnology is one of the seven Institutes of FORTH. IMBB’s aim is to promote scientific excellence in biological sciences. The Biosensors Lab focuses on acoustic wave biosensors, covering the whole range of device fabrication to bioanalytical and biological applications. Current research includes: (i) design of novel clinical assays based on acoustic wave devices for the detection of proteins in patients’ samples (e.g., for cardiovascular risk assessment), or genetic markers during hybridization assays (single nucleotide polymorphism detection in genetic diseases); (ii) the development of biophysical approaches for the structural and mechanical analysis of biomolecules and biomolecular interactions; (iii) the design of acoustic biosensors and integrated micro-systems for Lab-on-Chip (LOC) applications for the development of simple, versatile and sensitive diagnostic tools.